Keith E. Tansey, MD, Ph.D
Assistant Professor, Neurology and Physiology, Emory University School of Medicine Phone: 404.603.4274
Board Certification Neurology, Spinal Cord Injury Medicine Education and Training 2000 - 2002: Clinical Instructor - Neurorehabilitation, Research Fellow - Spinal Cord Injury, Department of Neurology, UCLA School of Medicine 1998 - 2000: Clinical Instructor - General Neurology, Research Fellow - Spinal Cord Injury, Department of Neurology, Washington University School of Medicine 1994 - 1998: Intern (Internal Medicine) and Resident (Neurology), Barnes-Jewish Hospital, Washington University School of Medicine 1985 - 1994: MD, PhD (Neuroscience), Medical Scientist Training Program, University of Texas Southwestern Medical School at Dallas, TX 1980 - 1985: BS (Biology), MS (Biomechanics), Stanford University, Palo Alto, CA Previous Academic and Professional Appointments 2002 - 2008: Assistant Professor, Departments of Neurology, Neurosurgery and PM&R, Director, Spinal Cord Injury Program, University of Texas Southwestern Medical Center at Dallas Professional Societies American Spinal Injury Association, National Neurotrauma Society, American Society for Neurorehabilitation, Society for Neuroscience, Ameican Academy of Neurology Honors and Awards 2008: Poster Session Award, Georgia Stem Cell Initiative Symposium 2007: Socrates Award, University of Texas Southwestern Medical Center 2007: Favorite Course Award for “Medical Neuroscience”, 1st Year Medical School Class, UT Southwestern Medical School 2006: Outstanding Teaching Award, Neurology Clinical Clerkship, UT Southwestern Medical School 2005: “Best Paper” Award, American Spinal Injury Association 2004, 2005, 2008: Outstanding Teacher Award, 1st Year Medical School Class, UT Southwestern Medical School 2001: Research Consortium Associate, Christopher Reeve Paralysis Foundation 1994: 'Neurology Prize' Award, UT Southwestern Medical School 1993: 'Texas Scholar' Award, Kent Waldrep National Paralysis Foundation Research Interests Dr. Tansey is interested in neural plasticity and repair that leads to functional recovery after spinal cord injury and how those processes could be improved. He is specifically interested in neural circuits for motor functions like locomotion but also neural circuits related to pain and autonomic nervous system function. He is working to combine interventions like activity based therapies with pharmacology, electrical stimulation, and cellular transplantation to improve neural recovery after injury. Dr. Tansey combines animal model and human research to gain better insight into these questions and to more rapidly translate basic science research ideas into clinical studies. Selected Publications Querry, R., Pacheco, F., Annaswamy, T., Goetz, L., Winchester, P. and Tansey, K.E., Synchronous stimulation and monitoring of the H-reflex during robotic body weight ambulation in subjects with spinal cord injury, J. Rehab. Res. & Dev. 45:175-186, 2008 McCoy, M., Martinez, T., Ruhn, K., Wrage, P. Keefer, E. Botterman, B.R., Tansey, K.E., and Tansey, M.G., Autologous transplants of Adipose-Derived Adult Stromal (ADAS) afford dopaminergic neuroprotection in a model of Parkinson's disease, Experimental Neurology 210:14-29, 2008 Petruska, J.C., Ichiyama, R.M., Crown, E.D., Tansey, K.E., Roy, R.R., Edgerton, V.R., and Mendell, L.M., Changes in Motoneuron Properties and Synaptic Inputs Related to Step Training Following Spinal Cord Transection in Rats J. Neuroscience 27:4460-71, 2007 McCoy, M.K., Martinez, T., Ruhn, K., Szymkowski, D., Smith, C., Botterman, B.R., Tansey, K.E. and Tansey, M.G., Blocking soluble Tumor Necrosis Factor signaling with dominant-negative Tumor Necrosis Factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson’s Disease, J. Neuroscience(Neurobiology of Disease section) 26:9365-9375, 2006 Winchester, P., McColl, R., Querry, R., Foreman, N., Mosby, J., Tansey, K., and Williamson, J., Changes in Supraspinal Activation Patterns following Robotic Locomotor Therapy in Subjects with Motor Incomplete Spinal Cord Injury. Neurorehabilitation and Neural Repair 19:313-324, 2005 Aimone, J.B., Leasure, J.L., Perreau, V.M., Thallmair, M & The Christopher Reeve Paralysis Foundation Research Consortium (Anderson, A.J., Arvanian, V.L., Bareyre, F.M., Bunge, M.B., Cotman, C.W., Craveiro, L., Crown, E.D., Edgerton, V.R., Engesser-Cesar, C., Gage, F.H., Garcia, A.J., Garraway, S.M., Horner, P.J., Howley, S., Ichiyama, R.M., Mendell, L.M., Moon, L.D.F., Moore, L., Parada, L.F., Pearse, D.D., Petruska, J.C., Romero, M.I., Schnell, L., Schwab, M.E., Tansey, K.E., Thuret, S.), Spatial and temporal gene expression profiling of the contused rat spinal cord. Exp. Neurol. 189:204-221, 2004 Faulkner, J.R., Hermann, J.E., Woo, M.J., Tansey, K.E., Doan, N.B., and Sofroniew, M.V., Reactive astrocytes protect tissue and preserve function after spinal cord injury. J. Neurosci. 24:2143-2155, 2004 Grant Support 2008 - 2011: NIDDR FIP “Evaluating the Effects of Activity-Based Therapy for Individuals with Chronic Spinal Cord Injury”, Co-Investigator 2008 - 2013: NIH-RO1 “Skeletal Muscle Plasticity, Fitness and Health after Spinal Cord Injury: Improving Glucose Tolerance”, Collaborator 2006 - 2011: NIH-RO1 “TNF Signaling in Neurodegeneration”, Collaborator 2005- 2008: Veteran's Administration Rehabilitation Research & Development, "Mechanisms of Neural Plasticity and Recovery in BWSTT after SCI", Co-Investigator 2003 - 2008: Mobility Foundation Center, UT Southwestern Medical Center, “Plasticity of Spinal Circuits after Injury”, Principal Investigator 2003 - 2008: Mobility Foundation Center, UT Southwestern Medical Center, “Robotic Locomotor Training in SCI”, Co-Principal Investigator 2005 - 2007: NIH-R21 “Neurogenic Potential of Progenitor Cells from Adipose”, Co-Investigator 2005 - 2007: Michael J. Fox Foundation, “Inflammatory Stimuli as ‘Second Hit’ Triggers for Development of Progressive Nigral Degeneration, Collaborator 2005 - 2007: American Health Assistance Foundation, “TNF Signaling in Alzheimer’s Disease Neuropathology”, Collaborator 2003 - 2005: Michael J. Fox Foundation, “The Role of TNF-mediated Dopaminergic Neurotoxicity in Parkinson’s Disease”, Collaborator 2003 - 2005: Texas Higher Education Coordinating Board Advanced Technology Program, “Genetically Engineered Transparent Biosynthetic Conduits for Directed and Enhanced Nerve Repair”, Co-Investigator 2003 - 2004: RehabNet-West, “Cortical Reorganization Following BWSTT for SCI”, Collaborator 2003 - 2004: National Parkinson Foundation, “Adipose-Derived Adult Progenitor Cells with Neurogenic Potential: An Alternate Tissue Source for Parkinson’s Disease Transplantation Strategies” |
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